Tag Archives: mRNA intracellularly integrates into DNA

Mar 7 2022

EMR Survey: Ivermectin Associated with Lower Mortality Than Remdesivir


Posted originally on TrialSite New by Staff March 5, 2022

EMR Survey Suggests Ivermectin Associated with Lower Mortality Than Remdesivir

A team of University of Miami researchers compared fatality rates for COVID-19 patients who took ivermectin and those who took remdesivir and found the ivermectin cohort experienced reduced mortality.

“Ivermectin use was associated with decreased mortality in patients with COVID-19 compared to remdesivir,” the authors wrote.

The authors determined that ivermectin’s odds ratio of mortality compared to Remdesivir was 0.308.

Ivermectin vs. Remdesivir

Ivermectin has been discouraged as an early treatment option by the United States Food and Drug Administration, Centers for Disease Control and other public health authorities, while remdesivir has been endorsed by those same authorities.

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“To our knowledge, this is the largest association study of patients with COVID-19, mortality and ivermectin,” said the authors. “Further double-blinded placebo-controlled [random controlled trials] with large samples are required for definite conclusion.”

University of Miami Research Team

The researchers included medical student Iakov Efimenko, medical student Sirpi Nackeeran, Sinan K. Jabori, MD, Associate Program Director of the Infectious Disease Fellowship Jose Gonzalez Zamora, MD; Sara Danker, MD, and Devinder Singh, MD, all of whom are affiliated with University of Miami’s Miller School of Medicine.

TriNetX Research Network Searched 

The team searched patient records on the TriNetX Research network, a federated electronic medical records network of over 44 healthcare organizations and 68 million U.S. patients from 2009 to 2021 to identify adults with a recorded COVID-19 infection between January 1, 2020, and July 11, 2021. 

The team then compared those with recorded use of ivermectin, but not remdesivir, against those with recorded use of remdesivir, but not ivermectin. 

The team also controlled for comorbidities and treatments that may affect COVID-19 survival outcomes: age, gender, race, ethnicity, nicotine use diabetes mellitus, obesity, chronic lower respiratory disease, ischemic heart diseases, tocilizumab, glucocorticoids, or ventilator use.

Mortality Primary Outcome

The group measured association with mortality as the primary outcome.

The team identified a cohort of 1,072 people who were treated with ivermectin and another 40,536 who were treated with remdesivir. 

In the ivermectin cohort, the average age was 51.9 + 17.8 years, 43% were male, 60% had glucocorticoids, and 1% required ventilator support, average age. 

In the remdesivir cohort, the average age was 62.0 + 16.0 years, 54% were male, 64% had glucocorticoids, and 2% required ventilator support. 

Ivermectin Reduced Mortality vs. Remdesivir by 70%

After using propensity score matching and adjusting for potential confounders, ivermectin was associated with 70 percent reduced mortality vs remdesivir with a risk difference of -5.224%.

Mar 4 2022

Study: Pfizer mRNA Vaccine Integrates Into Our DNA


Armstrong Economics Blog/Disease Re-Posted Mar 4, 2022 by Martin Armstrong

A new Swedish lab study shows that the mRNA vaccine integrates into our DNA at the cellular level – permanently.

Study abstract:

"Furthermore, a recent study showed that SARS-CoV-2 RNA can be reverse-transcribed and integrated into the genome of human cells. In this study, we investigated the effect of BNT162b2 on
the human liver cell line Huh7 in vitro. Huh7 cells were exposed to BNT162b2, and quantitative
PCR was performed on RNA extracted from the cells. We detected high levels of BNT162b2 in Huh7
cells and changes in gene expression of long interspersed nuclear element-1 (LINE-1), which is an
endogenous reverse transcriptase. Immunohistochemistry using antibody binding to LINE-1 open
reading frame-1 RNA-binding protein (ORFp1) on Huh7 cells treated with BNT162b2 indicated
increased nucleus distribution of LINE-1. PCR on genomic DNA of Huh7 cells exposed to BNT162b2
amplified the DNA sequence unique to BNT162b2. Our results indicate a fast up-take of BNT162b2
into human liver cell line Huh7, leading to changes in LINE-1 expression and distribution. We also
show that BNT162b2 mRNA is reverse transcribed intracellularly into DNA in as fast as 6 h upon
BNT162b2 exposure."

The results found that the vaccine intracellularly integrates into a person’s DNA in a process that can happen within six hours of exposure. Additionally, the mRNA vaccine does in fact travel to the liver and other locations such as ovaries. The messenger RNA travels outside of the nucleus to target proteins required for building cells (e.g., growing muscle tissue) in a process called transcription.

Scientists told us that the vaccine would not affect our DNA in any way. Rio Times reported, “For many years, Central Dogma of Molecular Biology stated that the “reverse transcription” — moving genetic code from RNA back into the sacred cellular nuclear and recoding the DNA — was impossible.” The compromised and biased scientific community eventually realized that reverse transcription was possible, as seen within the HIV RNA virus that does reprogram and replicate DNA.

Pfizer’s vaccine produces the LINE-1 enzyme, which is one of the enzymes required for reverse transcriptase. What does this mean for those who have taken this vaccine? There is growing concern that the vaccine is also affecting the “germ line,” which affects female eggs and male sperm cells, as well as forming fetuses. The long-term side effects of the vaccine have not been determined and the pharmaceutical companies have already lobbied governments to grant them full immunity for when those side effects are revealed.