Posted originally on TrialSite by Staff onDecember 4, 20212 Comments
Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Disease (NIAID) and chief medical advisor to the White House, presented with Centers for Disease Control and Prevention (CDC) director, Rochelle Walensky during the Press Briefings by the White House COVID-19 Response Team and Public Health Officials. Although Fauci could offer “no proof” that the vaccines will work on the Omicron variant of concern, Fauci declared that a booster dose of the COVID-19 vaccine should offer some amount of “cross-protection” against this new variant. Why would Fauci be so fast to come to this conclusion, given so many unknowns, from transmissibility to actual severity of the disease? America’s top doctor declared during this press conference that the health authorities should know more within “a matter of days to weeks.” But Fauci used this forum to again, emphasize the importance of using this presently unknown risk to get vaccinated. Meanwhile, WHO as of late last week reported so far no deaths from the Omicron variant of concern.
Fauci went on to show a presentation that purports to back his claims that a booster will help with omicron, despite the acknowledged lack of any proof at this point. Fauci continued, using the Delta variant as an example, saying that by September:
“Unvaccinated people in the United States had almost a six percent increased risk of getting infected and getting COVID-19 compared to fully vaccinated, and about 11-fold increased risk of being hospitalized, and a 14 increased risk of dying when you compare individuals who are fully vaccinated versus unvaccinated.”
Because “in vitro studies” indicate positive impact of boosters—“markedly,” increasing antibody titers “against a wide range of variants,” Fauci continues, positioning that it’s better to be safe than sorry declaring:
“One of the things we now know, and it’s becoming increasingly apparent, is that when you get a high level of antibody—and as shown in the slide in an animal model…when you look at the third dose, you increase the levels of neutralizing antibodies against all the variants.” Of course, this leads to “an increase in levels of memory B cells and T cells, which strongly suggest that boosters it will give you cross-protection against a number of variants.”
Fauci was summarizing data from different vaccines. With Moderna in people ages 18 to 64, titers rise from 55 to 872 by 28 days post the third jab, which is more than the rise after the second shot. Moreover, titers increase from 32 to 708 in elderly adults (65 and up) at 28 days after the boost.
Moreover, with BNT162b2 (Pfizer-BioNTech), the third shot boosts 50% serum neutralization titers to 1,321 from 241 in people ages18 to 55 while that same measurement spikes to 1,479 from 123 in the elderly (age 65 to 88)—all based on data from a piece in the New England Journal of Medicine.
But what about existing Antibodies?
The top doctor doesn’t utter a word about natural immunity and the risks of the vaccine, especially if people have higher amounts of antibodies. TrialSite recently covered growing reports of adverse events and the need for a COVID-19 vaccine adverse event patient advocacy organization.
The fear here is that few have their antibodies measured. In some cases, they may already be high, and a booster could potentially trigger an overreaction. As Fauci doesn’t raise the importance of natural immunity nor systematic measurement of antibody levels prior to a third inoculation, the true risk of the booster vaccine isn’t known. Moreover, we do not know if the booster vaccine will help with this new variant seemingly originating out of the southern region of Africa.