After Skool Published originally on Rumble on April 23, 2022
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This video explores some of the philosophies which examine the prioritization of safety. What happens when we value safety above all other values? I hope you all enjoy!
Geert Vanden Bossche, DVM, PhD General Manager at Voice for Science and Solidarity | The biggest challenge in vaccinology: Countering immune evasion
Posted originally on TS New on Jul. 22, 2022, 9:00 a.m.
Opinion Article
Intra-pandemic vaccination of toddlers with non-replicating antibody-based vaccines targeted at ASLVI[1]– or ASLVD[2]-enabling glycosylated viruses prevents education of innate immune effector cells (NK cells).
by Geert Vanden Bossche and Rob Rennebohm
Key message:
Antibody-based vaccines teach the immune system to produce high levels of antibodies that are directed against the surface protein that is responsible for initiation of viral infection. Due to their high specificity and strong binding capacity, these vaccinal antibodies (Abs) outcompete the child’s innate antibodies for binding to the virus[3]. This not only sidelines virus-neutralization by the natural innate immune system but also hampers the ability of innate antibodies to educate the innate immune system’s NK cells (Natural Killer cells) regarding NK cell recognition of (and appropriate response to) molecular self-mimicking patterns that are expressed on virus-infected host cells. This is particularly problematic when mass vaccination campaigns are conducted during a pandemic as those drive natural selection and dominant expansion of more infectious immune escape variants.
Strong immune priming as induced by vaccines elicits long-lived Ab titers. Even in the absence of further booster shots, repeated exposure to more infectious circulating variants will recall these vaccinal antigen (Ag)-specific Abs and thereby sustain high-titer antibody responses. When immature, low-affinity Abs become exposed to the virus, (which may occur when vaccines are administered during a pandemic), these Abs may bind to the virus without neutralizing it. This in its own right could already provoke Ab-dependent enhancement of infection (ADEI) by the target virus. Vaccinated toddlers are particularly at risk of ADEI as their innate immune system has not yet been trained. Consequently, young children who are vaccinated during a pandemic with non-replicating viral vaccines (directed at ASLVI- or ASLVD-enabling glycosylated viruses[4]) are at high risk of developing severe disease.
In addition, boosting of vaccinal Abs as a result of repeated exposure to more infectious immune escape variants will lead to prolonged suspension of NK cell education in these vaccinated toddlers. When, for a prolonged period of time, NK cells are prevented from being sensitized to pathogen-derived self-mimicking peptide patterns that are expressed on infected or otherwise pathologically altered cells, they may end up becoming tolerant to these patterns, which are typically shared among several different glycosylated pathogenic agents (G. Vanden Bossche, former provisional patent application). That is, the NK cells become hyporesponsive or desensitized to these pathogenic agents[5]. This opens the door to recognition by B and T cells of traditional antigens that are naturally expressed later on in the process of infection or pathologic alteration. Recognition by these ‘foreign-centered’ effector cells may enable abrogation but not prevention of infection (i.e., in the case of infectious pathogens) or lead to immune pathology (e.g., in the case of pathologically altered autologous host cells evolving towards expression of foreign proteins).
So, when the normal NK cell responsiveness to the patterns expressed on the surface of a specific glycosylated virus-infected cell (e.g. a SARS-CoV-2 infected cell) is downregulated, so is the NK cell response to largely homologous patterns on cells infected by other glycosylated viruses. That is how – in young children- vaccinal antibody-mediated interference with the education and response of NK cells regarding one particular ASLVI- or ASLVD-enabling glycosylated virus also interferes with the education and response of their NK cells regarding other glycosylated viruses causing ASLVI or ASLVD. This renders the vaccinated young child less able to handle not only the virus it got vaccinated against but also other glycosylated viruses (of course, unless that child got previously vaccinated with childhood vaccines comprising live attenuated glycosylated viruses such as measles, mumps, rubella, varicella, rotavirus). That is why/how vaccinated young children become more susceptible to other glycosylated viruses (besides the one they got vaccinated against).
The above-mentioned prolonged suspension of NK cell education, and the associated repetitive desensitization of NK cells, will not be ‘diluted’ by a “sporadic” sensitizing event (from an intercurrent influenza infection, e.g.).
The earlier this prolonged suspension of NK cell education occurs after the maternal Abs have waned, the more detrimental the effect will be. This is because it is during early childhood, when children have their greatest and most important capacity for education and practice of their innate immune system, that they ought to exploit this opportunity to actively kick off their own immune defense against ‘foreign’ while ensuring tolerance towards ‘self’. This opportunity occurs only once in a person’s life-time! Once the functional capacity of innate Abs wanes, the instructions conveyed to ‘self-centered’ innate immune cells (i.e., NK cells) on how to recognize self-mimicking patterns associated with ‘foreign’ as opposed to ‘self’ proteins may not be strong enough to prevent irreversible priming of ‘foreign-centered’ antigen-specific B and T cells. Once such priming has occurred, the child’s immune system will have irrevocably missed that small window of opportunity to draw the thinnest possible line between ‘self’ and ‘foreign’, enabling the immune system to discriminate ‘self’ from ‘self-mimicking’ (or ‘altered self’). If one leaves it up to the adaptive immune system, a line that thin will not be drawn as the adaptive immune system has only been conceived to distinguish ‘foreign’ from ‘self’. Deficient or insufficient education of ‘self-centered’ NK cells will therefore inevitably predispose the young child to immunopathologies (ranging from allergies over inflammatory diseases up to autoreactivity).
On the other hand, once their pre-priming has been properly established, ‘training’ of NK cells can take place at any later time. Training consists of imprinting immunological memory on pre-primed NK cells following their epigenetic reprogramming. Such functional reprogramming provides these cells with sufficient plasticity to establish an “adaptive” phenotype to meet the demands and challenges of altered environmental conditions (e.g., enhanced viral infectious pressure). However, innate immune effector cells cannot be trained unless they first got educated on how to recognize potential changes/ alterations they may need to adapt to. It goes, therefore, without saying that any intervention in this delicately evolving ecosystem cannot even be considered without an in-depth understanding of the mechanisms at play and the impact thereon of the targeted immune intervention.
[3] For the purpose of this manuscript, ‘virus’ relates to an ASLVI- or ASLVD-enabling glycosylated virus
[4] Examples of glycosylated viruses [other than SARS-CoV-2] causing ASLVI or ASLVDs: seasonal influenza, RSV, dengue virus and viruses responsible for vaccine-preventable infections: measles, mumps, rubella, varicella, rotavirus or other more virulent glycosylated viruses such as zoonotic influenza (e.g., avian influenza virus), parapox virus (e.g., smallpox virus), Ebola virus, Marburg virus
[5] The biological mechanism for this fine regulation of the NK cell response is due to downregulation of germline encoded “activating receptors” on NK cells, and/or upregulation of “inhibitory receptors” on NK cells, and/or hypo-responsiveness to “activation signaling.” More details on the underlying mechanisms of this fine regulation of NK cells can be found in the literature as , for example, published by Orr, Mark T., and Lewis L. Lanier. “Natural killer cell education and tolerance.” Cell 142.6 (2010): 847-856 and Perera Molligoda Arachchige AS. Human NK cells: From development to effector functions. Innate Immunity. 2021;27(3):212-229.
Posted originally on the conservative tree house on July 23, 2022 | sundance
Considering that I have yet to absorb, or accept, the increasingly likely possibility of society normalizing people eating bugs, the looking over-the-horizon folks at the New York Times just, well, stopped me in my tracks. I did not have eating people on my Biden consequences bingo card.
I know Biden/Obama’s beloved Davos crowd (World Economic Forum) love to hold meetings about how their social engineering will create a “new normal” for everyone but themselves; however, I mean, c’mon, even for the furthest left this has to be a bridge too far, no?
Is the Biden era of transformational social change really going to go combine: defining “essential workers”, forced medical procedures, radical climate change, the eating of bugs and insects, post-birth abortion and chopping the genitals off children without parent consent, together with the social acceptability of cannibalism; all of it, into one term in office?
It appears the January 6th committee has prevented Stephen K. Bannon from showing his evidence and the right to defend himself including his protection of the executive privilege from the President.
It is suggested he will be found guilty as soon as today and his case then rests on the slim ‘chance’ of the Supreme Court taking the case.
Would you kindly unpack this entire debacle when this committee is not even a court of law in a courtroom, please?
It is shaping up for President Trump to be charged, right on time for the midterms.
Thank you In advance for any clarity you can provide on the latest abuse of power by the legal system and the Justice Department.
RH
ANSWER: The Democrats and Liz Cheney are intent upon criminally charging Trump with insurrection. They need to prevent Trump from running in 2024. This is not about jail time. This will make the headlines for the mid-term, and this is their Hail Mary play to paint all Republicans as evil and should be thrown out of office. Of course, they are instigating revolution, for our computer points to civil war in the US. I believe this is part of the reason our computer is targeting 2023 as a Political & Geopolitical Year from Hell. Of course, the Democrats who foam at the mouth and live for the day that they can completely eradicate all opposition are blind to history and the consequences of their own actions.
The Insurrection Clause was part of the 14th Amendment passed after the Civil War to prevent anyone from the South from holding office again. This is what they are relying on, and it is really absurd. Trump felt the election was rigged, but that did not lead to a civil war – YET! There are two outcomes here, and both lead to civil war. The ONLY way Trump could be indicted for this would be under the questionable theory of a “conspiracy to commit an insurrection,” which the Constitution does not support as a bar. So they are looking for headlines — not reality. The Justice Department will do whatever the Democrats demand. It is no longer a viable institution. When the rule of law collapses, the ONLY resolution is civil war. The history of Rome shows that endlessly.
This is being done for the midterms — NOT for 2024. They know this would allow Trump ample time to appeal, and the Supreme Court would take that one. Thus, the Democrats know this is an abuse of power, but they do not care. They have so divided the country there is just no return to normal — EVER! I really wish this was not the case. But it is getting time to turn out the lights on this Republic experiment. Oh, how the fools we have in Washington refuse ever to consult history. Indeed, it is often said that when Franklin was asked what kind of government they created, he wittingly said: “A republic, if you can keep it.”
Whether that is true or not is really irrelevant. Republics never last because they are the easiest to corrupt, for the “representatives” can be bought like NASCAR drivers, but they do not wear a patch to show who bought them. I have been in the halls of Capitol Hill, and when I was with the government under Maggie Thatcher, all you saw were lobbyists everywhere. I remember seeing US people in London supporting Tony Blair, trying to spread their Marxist agenda just as Russia once claimed they would bury us with their Marxist agenda.
The Justice Department would indict Trump, but nobody would actually violate the law by threatening the Supreme Court over abortion, which is not a Constitutional Right under due process and more than euthanasia, or demanding you have a human right to some medical treatment and the government must pay for it. The Supreme Court has held that the Constitution is NEGATIVE, not POSITIVE, and its decision in Harris v McRae illustrated how wrong Roe v Wade was decided. That was a very clever mental manipulation when Justice Ginsberg said Roe was really about reducing population, so you tell the women it is a right to abort, and they protest for that fictional right when they have been manipulated by the Gates Foundation & Rockefeller Foundation that have always supported killing off minorities. They have already brainwashed so many women who think this is a right when in fact they are mindless drones doing the bid of Gates and the Rockefellers.
This is all part of the process of destroying the United States. We cannot live as one nation divided with such hatred. We are becoming Ukraine with a mindless civil war based entirely upon sheer seething hatred of Russian-speaking Ukrainians. There is no going back for Ukraine, and there will be no return to normal for the United States. We will most likely divide along the same lines as North v South. The hatred of state’s rights v federalism will return.
There have been some bad decisions by the Supreme Court, such as Dread Scott and allowing the Japanese imprisonment during WWII. But never in the history of the nation has what is unfolding over abortion ever taken place, which is in itself, a confirmation that our computer is forecasting that the United States will separate. It has become impossible to live together. The left just hates the right, and it is always the LEFT, as in the Communist Revolutions, that end up waging war and justify the slaughter of anyone who they disagree with.
The ONLY way to secure the future is to divide the United States between LEFT and RIGHT. There are many who personally have no desire to be an economic slave for policies I do not agree with on an economic and RELIGIOUS basis. Even the progressive tax policies of the left violate the Ten Commandments, which is an affront to the religious beliefs of many.
Equal Rights is precisely that. They somehow are eliminated if it comes to material wealth. An A student should be reduced to a C student because it is not fair that an F student should fail. They should be given a C, so everyone is equal regardless of talent. That worked well for communism.
Ironically, the entire issue of legalizing gay marriage was because of the tax code. Any couple who lives together and contributes to a relationship should be treated the same as a married couple because it is economic equality, be they gay or just a common-law type marriage. It is always the hunt for taxes that creates inequality.
Fauci plans to retire as soon as Biden leaves office as he knows he will no longer be protected. He mistakenly believes that he is above the law and will not be prosecuted for his crimes against humanity. Rand Paul, Fauci’s longtime foe, made it very clear that Republicans will subpoena Fauci if they take back the House or the Senate. Paul is not afraid to come off as a “conspiracy theorist” and plainly stated he wanted to know if there was a cover-up involved.
“I do fully believe this virus, this pandemic that killed 6 million people around the world, leaked from the lab. But I think there was a concerted effort by him and his colleagues to cover this up and make sure it didn’t come to light, that the NIH was funding that lab and that there was reasonable scientific evidence that suggests that it came from the lab. So he’s going to be made to testify under oath. And I hope he sticks around because we do have some questions.”
Paul is not alone in his desire to investigate Fauci. Rep. Madison Cawthorn (R-N.C.) vowed to prosecute Fauci is the House gains control during the midterm elections. “We want to prosecute this guy to the full ability of the law. And I’ll tell you, to lie to the American people just to get your name in the news, just to get your face on the cover of books, just to get fame and fortune. I’ll tell you, Dr. Anthony Fauci does not deserve either fame or fortune,” he continued. Cawthorn also accused Fauci of being a “pawn of the Chinese Communist Party” and lying under oath about his knowledge on gain-of-function research.
Rep. Marjorie Taylor Greene introduced the “Fire Fauci Act” in April 2021 which brings to light many valid questions. Why is Dr. Fauci the highest-paid government employee, surpassing even the income of the president? How much did he profit from the pandemic? Why did he claim herd immunity would require up to 85% of the population to be vaccinated when there is no proof or study to support this idea?
If the Republicans takeover during the midterm elections, expect Dr. Anthony Fauci to face a trial. The public at large will then learn the lies being pushed as science and will realize that the entire pandemic was a manufactured event. This will lead to civil unrest on a widescale spanning far beyond America.
The Centers for Disease Control and Prevention (CDC) will no longer report COVID outbreaks on cruise ships. Per the CDC’s website:
“As of July 18, 2022, CDC’s COVID-19 Program for Cruise Ships is no longer in effect. CDC will continue to publish guidance to help cruise ships continue to provide a safer and healthier environment for passengers, crew and communities going forward.”
Clearly, this is an attempt to hide the fact that the vaccinated are spreading and contracting COVID, possibly more frequently than the unvaccinated. Nearly all cruise liners have required staff and passengers to be “fully vaccinated” before boarding. Yet, there are countless stories of COVID outbreaks on ships with 100% vaccination rates. So the cruise industry lost over $63 billion between 2020 and 2021 for absolutely no reason.
The CDC still recommends that vacationers take a COVID test before boarding and adhere to all their guidelines. The agency now claims that the liners simply have access to their guidance and they no longer need to control the situation. In reality, they cannot explain why ships containing fully vaccinated passengers and staff are experiencing outbreaks. Answer: THE VACCINE DOES NOT WORK!
Dr. Anthony Fauci, Mr. COVID himself, announced that he would retire at the end of Joe Biden’s term. Fauci hinted in an interview that he fears an investigation into his personal dealings if the conservatives take back control next year. “They’re going to try and come after me, anyway. I mean, probably less so if I’m not in the job,” Fauci told Politico. We know the vaccination does not work and causes more harm than good. The long-term effects of the vaccines and lockdowns are now coming to light, and Fauci is responsible as the mascot for the entire COVID agenda.
Fauci maintains that boosters will be necessary every year, similar to the flu vaccine, despite the components of the two vaccines differing drastically. Fauci also admitted that the people are waking up to the fear-mongering and brainwashing techniques he used to scare the world to stay inside.
“It’s becoming more and more difficult to get people to listen, because even the people who are compliant want this behind them,” Fauci said, bewildered that people do not obey his every word. “What I try to convince them [of], with my communication method, is we’re not asking you to dramatically alter your lifestyle. We’re not asking you to really interfere with what you do with your life. We’re just asking you to consider some simple, doable mitigation methods.”
The ”simple, doable mitigation methods” involved involuntary house arrest, school closures, business closures, and forced vaccinations of an EXPERIMENTAL mRNA gene-altering therapy. These policies were a gut punch to the global economy. Countless people lost their jobs and lives due to his warped God-complex view of “trust the science.” This man should be held accountable for the damage he has done to society – permanent damage that will linger for generations to come.
Posted originally on the conservative tree house on July 15, 2022 | sundance
The Humane Society of Virginia is trying to find homes for 4.000 beagles, exactly two weeks after NIAID Director Anthony Fauci told congress he would no longer use beagles for allergy testing.
These two stories seem connected.
July 5, 2022 – Under fire from foes of federal animal testing, the agency headed by COVID-19 czar Anthony Fauci has canceled a plan to start new tests of allergy medicine on beagles, some as young as 6 months.
In a letter to Sen. Joni Ernst (R-IA) and promoted by the White Coat Waste Project, Fauci said that instead of dogs, the new hay fever drug will be tested on rodents.
“Although the contract to Inimmune Corporation proposed the use of murine and canine preclinical animal models, after consultation with the U.S. Food and Drug Administration, the company elected to proceed using two rodent models only,” wrote Fauci, the director of the National Institute of Allergy and Infectious Diseases. “No experiments utilizing the canine model are being conducted under this contract.”
[…] The letter was a big victory for Ernst and the animal rights group, which had started a popular hashtag campaign against the testing: #BeagleGate. (read more)
Yesterday, this next story surfaced:
July 15, 2022 – CUMBERLAND, Va. — The Humane Society of the United States says it is working fast to transfer thousands of dogs bred for medical research from a facility in Virginia.
On Wednesday, the Humane Society said that over the course of 60 days, they’d be transporting around 4,000 beagles in stages to shelters nationwide so they could be adopted. (read more)
4,000 beagles?
Good grief, is that the scale of Anthony Fauci’s beagle abuse?
QUESTION: Marty, You have forecasted that your disease model turned up here in 2022. COVID was exploited, but it was no worse than the flu. Then there is monkeypox. But the latest is the much more lethal Marburg virus in Africa. Is this going to be the real one?
DC
ANSWER: The model did not target a specific virus. There are serious outbreaks throughout history but they are not always the same virus or bacteria. The history of this particular virus only goes back to 1967. This particular virus has a base cycle of 5-year intervals. The major outbreak was 2004-2005 which lasted into 2008. Ideally, our model projected that would reappear in 2013 and it showed up in 2012 a little ahead of schedule.
A major outbreak should come in the 2027-2028 time period. But keep in mind that this has not turned into a pandemic and has been confined to Africa. It is spread through bodily fluids so which usually involves sex or touching an open sore. So I would not be concerned that this will spread to your neighborhood without human intervention. The most devastating disease cycle will be from 2027 into 2050.
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This is a library of News Events not reported by the Main Stream Media documenting & connecting the dots on How the Obama Marxist Liberal agenda is destroying America
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